Web“cPWWP2A-miR-579-Angiopoietin 1/Occluding/SIRT1” in DR. This study may provide new insight into the potential use the cPWWP2A-miR-579 as new treatment strategies for … WebMar 17, 2024 · These results suggest that cPWWP2A is a molecular sponge for miR-29b. To verify that cPWWP2A/miR-29b regulates the NLRP3 signaling pathway, C2C12 cells …
Targeting pericyte-endothelial cell crosstalk by circular RNA …
WebMar 26, 2024 · The sequence of cPWWP2A obtained by Sanger sequencing was consistent with the sequence of cPWWP2A annotated in circBase (Fig. 1B). cPWWP2A was resistant to RNase R digestion, whereas linear PWWP2A mRNA was easily degraded (Fig. 1C). qRT-PCR assays showed that retinal cPWWP2A expression was significantly higher in … WebMay 16, 2024 · For example, circRNA cPWWP2A could upregulate the expression of occludin, angiopoietin-1, and sirtuin-1 (markers regulating retinal vascularization and endothelial cell function), thereby ... hofors camping
circRNA_010383 Acts as a Sponge for miR-135a, and Its …
WebPericyte-derived cPWWP2A affects pericyte coverage and vascular integrity through interacting with miR-579 and its target genes, including angiopoietin 1/occludin/SIRT1. Our study thus reveals a critical role of cPWWP2A-mediated signaling in retinal microvascular dysfunction and implies potential therapeutic benefit with high-level expression ... WebMar 21, 2024 · Protein attributes for PWWP2A Gene. Size: 755 amino acids. Molecular mass: 81960 Da. Protein existence level: PE1. Quaternary structure: Component of a … WebIntroduction. Diabetes mellitus is a chronic disease worldwide. According to an epidemiological survey released by the World Health Organization, the global prevalence of diabetes among adults (20–79 years) will increase from 6.4% in 2010 to 7.7% in 2030, which means that the number of affected adults will increase from 285 million to 439 million. 1 … huawei cloud snapshot connection