WebAlwash, S. M., McIntyre, H. D., & Mamun, A. (2024). The association of general obesity, central obesity and visceral body fat with the risk of gestational diabetes mellitus: Evidence from a systematic review and meta-analysis. WebMicrosequencing of the 43- and 48-kDa proteins that copurified with Orc1p and Orc2p led to their identification as the Orc4p and Orc5p subunits, respectively. Peptide sequences from …
Cell cycle-dependent localization of Orc2p and Mcm7p at human ...
WebThe origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast … WebHuo et al., 2012; Wu et al., 2024), we found that Orc1p, Orc2p, Orc5p, and Orc6p have self-interactions, i.e., molecules of the same subunit interact with each other (Figure 1A). Of note, yeast two-hybrid analysis based on the relative yeast growth rates on different selection stringencies, as we used in this study, favors sickness absence procedure mitie
Linkage between phosphorylation of the origin recognition complex an…
WebFeb 6, 2009 · Adenine nucleotides that bind to the origin recognition complex (ORC) are also suggested to be involved in this process. Of the six subunits of the Saccharomyces … WebDec 1, 2007 · These results suggest that 2p-3p-6p may form a core complex. Orc2p and Orc6p are phosphorylated in vivo, regulating initiation of DNA replication. However, replacing the phosphorylated amino acid residues with others that cannot be phosphorylated, or that mimic phosphorylation, did not affect subunit interactions. WebTo determine whether Orc1p, Orc2p, and Orc4p also formed a complex in these somatic cells, we performed the same immunoprecipitation using anti-Orc1p mAb TK15 and anti-T antigen mAb423 as a control. TK15 specifically immunoprecipitated Orc1p, Orc2p, and Orc4p from the somatic cell extract (Fig. 4 C ), arguing that a very similar ORC is also ... the phunsukh wangdu