WebbLipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group of pharmaceuticals that are used to lower the level of lipids and lipoproteins such as cholesterol, in the blood (hyperlipidemia).The American Heart Association recommends the descriptor 'lipid … WebbHigh-intensity statin therapy (atorvastatin 40–80 mg or rosuvastatin 20–40 mg) is recommended for most of these patients, and moderate-intensity statins for the remaining groups. 17 The new 2013 ACC/AHA guidelines match statin assignment to total plaque burden better than the older guidelines, with only a modest increase in the number of …

Lipitor - Food and Drug Administration

Webb12 aug. 2024 · Brand name: Lipitor. Atorvastatin only comes in the form of a tablet you take by mouth. Atorvastatin oral tablet is used to improve cholesterol levels and decrease … Webb20 jan. 2024 · Types of statins Statins are available under a variety of generic and brand names, including: atorvastatin (Lipitor) fluvastatin (Lescol) lovastatin (Mevacor, Altoprev) pitavastatin (Livalo)... diameter of 225 60 16 tire

National Center for Biotechnology Information

Webb20 juli 2024 · Simvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body. WebbAbsorption. Peak plasma concentrations of both active and total inhibitors were attained within 1.3 to 2.4 hours post-dose. While the recommended therapeutic dose range is 10 to 40 mg/day, there was no substantial deviation from linearity of AUC with an increase in dose to as high as 120 mg. Relative to the fasting state, the plasma profile of inhibitors … Atorvastatin, sold under the brand name Lipitor among others, is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. For the prevention of cardiovascular disease, statins are a first-line treatment. It is taken by mouth. Common side effects include joint … Visa mer The primary uses of atorvastatin is for the treatment of dyslipidemia and the prevention of cardiovascular disease: Dyslipidemia • Hypercholesterolemia (heterozygous familial and nonfamilial) … Visa mer Major • Type 2 diabetes is observed in a small number of people, and is an uncommon class effect of all statins. However, the benefits of statin … Visa mer Absorption Atorvastatin undergoes rapid absorption when taken orally, with an approximate time to maximum … Visa mer The first synthesis of atorvastatin at Parke-Davis that occurred during drug discovery was racemic followed by chiral chromatographic separation of the enantiomers. … Visa mer • Active liver disease: cholestasis, hepatic encephalopathy, hepatitis, and jaundice • Unexplained elevations in AST or ALT levels • Pregnancy: Atorvastatin may cause fetal harm by affecting … Visa mer As with other statins, atorvastatin is a competitive inhibitor of HMG-CoA reductase. Unlike most others, however, it is a completely synthetic compound. HMG-CoA reductase catalyzes … Visa mer Several genetic polymorphisms may be linked to an increase in statin-related side effects with single nucleotide polymorphisms (SNPs) in the SLCO1B1 gene showing a 45 … Visa mer circle ch class 9